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Bioactive
Peptides
Prices
for individual peptides range from $50/mg to $950/mg, depending upon the
purity level and the sequence. Peptides
are available at purity levels of >70%, >85% and >95%.
For a specific peptide, please contact Customer Service by e-mail (support@geno-mechanix.com)
or by telephone (904-462-2249).
Cardio
Peptides
eM-P056
Cardioexcitatory peptide from the African giant
snail
SGQSWRPQGRF- NH2
Biochem. Biophys. Res. Comm., 167, 777 (1990).
eM-P093
Small Cardioactive Peptide A
(SCPA)
ARPGYLAFPRM- NH2
P.E. Lloyd et al., Peptides 8,179 (1987).
eM-P094
Small Cardioactive Peptide B
(SCPB)
MNYLAFPRM- NH2
P.E. Lloyd et al., TINS 9, 428 (1986).
Eosinophilotactic
Peptides
eM-P095
AGSE
E.J. Goetzl and K.F. Austen, PNAS 72,
4123 (1975).
eM-P096
VGDE
eM-P097
VGSE
E.J. Goetzl and K.F. Austen, PNAS 72,
4123 (1975).
Fibroblast
Growth Factor
(FGF)
Inhibitory Peptides
eM-P098
APSGHYKG
A.Yayon et al., Proc. Natl. Acad. Sci. USA 90,
10643 (1993).
eM-P099
KRTGQYKL
A.Yayon et al., Proc. Natl. Acad. Sci. USA 90,
10643 (1993).
Inflammatory
Related Peptides
eM-P053
Antiflammin-I
MQMKKVLDS
Phospholipase A inhibitor; inhibits synthesis of
platelet activating factor
eM-P086
Anti-Inflammatory Peptide II
HDMNKVLDL
L. Miele et al., Nature 335, 726 (1988).
eM-P087
Anti-Inflammatory Peptide III
MQMNKVLDS
L. Miele et al., Nature 335, 726 (1988).
eM-P088
Anti-Kentsin
TRLR
Leucokinins
eM-P052
Leucokinin I
DPAFNSWG- NH2
Neuropeptide from Madeira cockroach Leucophaea
maderae; stimulates contraction of lower digestive
tract
Holman, G.M., et al., Comp. Biochem. Physiol.
C, 84,
205 (1986).
eM-P083
Leucokinin II
DPGFSSWG- NH2
G.M. Holman et al., Comp.
Biochem. Physiol. 84C,
205 (1986).
eM-P085
Leucokinin III
DQGFNSWG- NH2
G.M. Holman et al., Comp. Biochem. Physiol. 84C,
271 (1986).
Neuropeptides and
related peptides
eM-P064
Angiotensin (Human)
DRVYIHPFHL
eM-P066
Bradykinin
RPPGFSPFR
eM-P067
B-casomorphin (Human)
YPFPGPI
R. Greenberg et al., J. Biol. Chem. 259, 5132 (1984).
eM-P060
DSIP; Sleep inducing peptide
WAGGDASGE
Schoenenberger, G.A., and Monnier, M.,
Proc. Natl. Acad. Sci. USA, 74, 1282 (1977).
Kafi, S., et al., Neurosci. Lett., 13, 169 (1979).
Monnier, M., et al., Experientia, 33, 548 (1977).
eM-P068
Endomorphin-1
YPWF- NH2
This peptide is a potent and selective endogenous
agonist for the mu-opiate receptor.
J.E. Zadina et al., Nature 386, 499 (1997).
H.C. Champion et al., Peptides 18, 1393 (1997).
eM-P069
Endomorphin-2
YPFF- NH2
This peptide has a high affinity and specificity
for the mu-opiate receptor. It
has potent mu-
selective bioactivity, including analgesia.
J.E. Zadina et al., Nature 386, 499 (1997)/H.C.
Champion et al., Peptides 18, 1393 (1997).
eM-P063
Enterostain (Human)
APDPR
eM-P071
Gluten exorphin A5
GYYPT
S. Fukudome et al., Peptide Chemistry 1991,
A.Suzuki, ed., Protein Research Foundation,
Osaka, p. 345 (1992)/S. Fukudome and M. Yoshikawa,
FEBS Lett. 296, 107 (1992).
eM-P072
Gluten exorphin B5
YGGWF
S. Fukudome et al., Peptide Chemistry 1991,
A.Suzuki, ed., Protein Research Foundation, Osaka,
p. 345 (1992)/S. Fukudome and M. Yoshikawa, FEBS
Lett. 296, 107 (1992).
eM-P073
Gluten exorphin C
YPISL
C. Zioudrou et al., J.Biol. Chem. 254, 2446 (1979)
F.R. Huebner et al., Peptides 5, 1139 (1984)
S. Fukudome et al., Peptide Chemistry 1991,
A.Suzuki,
ed., Protein Research Foundation,
Osaka, p. 345 (1992).
S. Fukudome and M.
Yoshikawa, FEBS Lett/316, 17 (1993).
eM-P076
Kassinin
DVPKSDQFVGLM- NH2
Peptide of the tachykinin family
A.Ajnastasi et al., Experientia 33, 857 (1977).
eM-P077
Kininogen Based Thrombin Inhibitor Analog
FQVVCG- NH2
eM-P070
Leu-enkephalin
YGGFL
J.hughes et al., Nature 258, 577 (1975).
eM-P043
g1-Melanocyte Stimulating Hormone (MSH)
YVMGHFRWDRF- NH2
eM-P044
g2-Melanocyte Stimulating Hormone (MSH)
YVMGHFRWDRFG- NH2
S. Nakanishi et al., Nature 278, 423 (1979).
eM-P045
d-Melanocyte Stimulating
Hormone (MSH)
SMEVRGW
eM-P074
Metorphamide
YGGFMRRV- NH2
An octapeptide found in bovine brain and adrenal tissue.
It is the only endogenus opioid peptide with high affinity
for m opioid receptors.
H. Matsuo et al., Nature 305, 721 (1983)/E. Weber et al.,
Proc. Natl. Acad. Sci. USA 80, 7362 (1983)/P.D. Marley
et al., Brain Res. 363, 10 (1986)/M. Sonders and E.
Weber,
J. Neurochem. 49, 671 (1987).
eM-P041
Neurokinin A (Neuromedin L, Substance K)
HKTDSFVGLM-NH2
H. Nawa et al., Nature 306, 32 (1983)
eM-P042
Neurokinin B (Neuromedin K)
DMHDFFVGLM- NH2
K. Kanagawa et al., BBRC 114, 533 (1983)
eM-P065
Neuropeptide FF
FLFQPQRF- NH2
H.Y.T. Yang et al., PNAS 82, 7757 (1985)
eM-P061
Opiate antagonist
YPKG- NH2
Interacts with GABAergic and dopaminergic systems
Hackler, L., et al., Peptides, 15, 945
(1994).
eM-P054
Ranakinin
KPNPERFYGLM- NH2
NK1 tachykinin receptor antagonist
O’Harte, F., J. Neurochem., 57, 2086 (1991).
eM-P078
Ranamargarin
DDASDRAKKFYG- NH2
This tachykinin has an activity profile like substance
P and physalaemin.Y.Q.
Tang et al., Regul. Peptides
22, 182 (1988).
eM-P079
Ranatachykinin A
KPSPDRFYGLM- NH2
This peptide shows sequence homology to other known
tachykinins and elicits strong effects in the guinea-pig
ileum and rat duodenum contractility assays in an
eledoisin-like manner.
K.Kangawa et al.,
Regul. Peptides 46, 81 (1993).
eM-P046
Substance P
RPKPQQFFGLM- NH2
eM-P080
Urechistachykinin I
LRQSQFVGSR- NH2
eM-P081
Urechistachykinin II
AAGMGFFGAR- NH2
These two tachykinin-related neuropeptides have
high sequence homology with those of the vertebrate
and insect tachykinins. They
potentiate spontaneous
rhythmic contractions of the cockroach hindgut.
T. Ikeda et al., Biochem. Biophys. Res. Commun.
192, 1 (1993).
eM-P075
Valorphin
VVYPWTQ
This peptide corresponds to residues 32-38 of the Beta
chain of bovine hemoglobin and possesses some opiate
activity.
V. Brantl et al., Eur. J. Pharmacol. 125, 309 (1986)
T.P. Davis et al., Peptides 10, 747 (1989)/E.-L. Glamsta
et al.,
Regul. Peptides 34, 169 (1991)/J.Erchegyi et al.,
Int. J.
Peptide Protein Res. 39, 477 (1992)
Protein
Kinase Related Peptides
eM-P051
High-affinity substrate for cAMP-dependent protein
kinase
RTKRSGSVYEPLKI
Murray, K.J., et al., Biochem J., 267, 703 (1990).
eM-P050
Inhibitor of cGMP-dependent protein kinase
RKRARKE
Glass, D., et al., Biochem. J., 213, 159 (1983).
eM-P049
Substrate for cAMP dependent
protein kinase;
histone H1 phosphorylation site
RRKASGP
Pomerantz, A.M., et al., Proc. Natl. Acad. Sci. USA,
74, 4261 (1977).
eM-P047
Substrate for tryrosine protein kinase
RRLIEDAEYAARG
Pike, L.J., et al., J. Biol. Chem., 261, 3782 (1986).
Casnellie, J.E., et al. Proc. Natl. Acad. Sci. USA,
79, 282 (1982).
eM-P048
Substrate for tryrosine protein kinase
RRLIEDNEYTARG
Krebs, E.G., et al. Proc. Natl. Acad. Sci. USA,
79, 1443 (1982).
Viral
Peptides
eM-P103
Herpes Virus Ribonucleotide Reductase Inhibitor
YAGAVVNDL
eM-P104
HIV Integrase Inhibitor
HCKFWW
R.A.P. Lutzke et al., Proc. Natl. Acad. Sci. USA,
92, 11456 (1995).
Miscellaneous
Peptides
eM-P084
Angiotensin Converting Enzyme (ACE) inhibitor
PTHIKWGD
Y. Kohama et al., BBRC 155, 332 (1988).
eM-P057
Active site peptide of
penicillin-binding protein
1b
from Escherichia coli.
SIGSLAK
Nicholas, R.A., et al., Biochemistry, 26, 3448 (1985).
eM-P090
Calcium-like peptide
VAITVLVK
Dillon, J. et al., Proc. Natl. Acad. Sci. USA,
88, 9726 (1991).
eM-P091
Calmodulin Kinase II substrate
(Syntide 2)
PLARTLSVGLPGKK
eM-P092
Carbohydrate Structure Mimicking Peptide
APWLYGPA
R. Hoess et al., Gene 128, 43 (1993).
eM-P106
Entero-kassinin
DEPNSDQFIGLM- NH2
L. Negri et al., Regul. Peptides 22, 13 (1988).
eM-P100
Hamburger Pentapeptide
(Human IgE
Pentapeptide,
HEPP, IgE (330-334))
DSDPR
eM-P101
Hamburger Pentapeptide Analog
(Human IgE
Peptide,
IgE (330-334) analog)
ADSDGK
eM-P102
Heparin Binding Protein
(Fibronectin Adhesion-
Promoting Peptide)
WQPPRARI
K.L. Hines et al., Proc. Natl. Acad. Sci. USA,
91, 5187 (1994)
A. Woods et al., Molecular Biology of the Cell 4,
605 (1993).
eM-P102
Heparin Binding Protein
(Fibronectin Adhesion-
Promoting Peptide)
WQPPRARI
K.L. Hines et al., Proc. Natl. Acad. Sci. USA,
91, 5187 (1994)
A. Woods et al., Molecular Biology of the Cell 4,
605 (1993).
eM-P089 Histatin-8
(Hemagglutination-Inhibiting
Peptide (HIP))
KFHEKHHSHRGY
F.G. Oppenheim et al., J. Biol. Chem. 263,
7472 (1988).
eM-P062 Immunostimulating peptide from human caseins
VEPIPY
Gatogno, L., et al., Immunol. Lett., 18, 27 (1988).
eM-P082 Laminin Binding Inhibitor
LGTIPG
D.D. Hunter et al., Nature 338, 229 (1989).
eM-P105 Locustakinin I
AFSSWG- NH2
G.M. Coast, Peptides 17, 327 (1996).
eM-P058 Thrombin Receptor Activator
SFLLRNPNDKYEPF
Vu, T.K.H., et al., Cell, 64, 1057 (1991)./Vassallo,
R.R., et al., J. Biol. Chem., 267, 6081 (1992).
eM-P059 TRH-Potentiating peptide
SFPWMESDVT
Potentiates the TRH-induced release of TSH from
the
anterior pituitary.
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