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  5' or 3' End Modified Oligonucleotides

Price for purification is per oligo and added to the per base cost.
Synthesis Scale (µmole) Primary Amine Fluorescein/
6-FAM
TAMRA HEX, TET, ROX, JOE Biotin Digoxigenin
0.05 $20.00 $80.00 $85.00 $85.00 $45.00 $90.00
0.10 25.00 85.00 90.00 90.00 50.00 100.00
0.20 30.00 90.00 95.00 95.00

55.00

110.00
1.00 40.00 110.00 125.00 125.00 75.00 150.00


Synthesis Scale (µmole) Phosphate 5'-
Carboxyl
3'-
Carboxyl
3'-Dideoxy A/C/G/T 3'-
Dinitrophenyl
0.05 $20.00 $60.00 $50.00 $70.00 $70.00
0.10 25.00 65.00 55.00 80.00 75.00
0.20 30.00 70.00 60.00 100.00 85.00
1.00 35.00 80.00 70.00 200.00 100.00


Synthesis Scale (µmole) 5'-
Cy5/Cy3
3'-
Cy5/Cy3
5'- or 3'- Cy5.5/Cy2   Acridine Psoralen (C2/C6)


EDANS/
DABCYL

0.05 $75.00 $200.00 $200.00 $90.00 $100.00 $90.00
0.10 75.00 210.00 210.00 100.00 110.00 100.00
0.20 75.00 220.00 220.00 110.00 120.00 110.00
1.00 125.00 250.00 250.00 125.00 150.00 125.00

All prices listed above are per base for unpurified oligonucleotides – Desalted, Lyophilized.  

Add the following costs for purification per oligonucleotide:

OPC cartridge - $20.00
HPLC/PAGE - $75.00


We make many other modifications.  Common examples:

Phosphorothioate 5’®5’ or 3’®3’ Linkages
Methylphosphonate Modifications/Spacers (C3, C9, C18)
Deoxy Inosine d-Spacer
  d(N)6-15-Non-equimolar Base Mixtures

Please contact us:

  • for a modified oligonucleotide
  • for synthesis in excess of 1µmole
  • if you have a minimum requirement
  • if you do no't see what you are looking for








 
 
 

  
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