GenoMechanix is the solution to your custom molecular tools in:

• GENOMICS
   * Custom DNA probes/primers
   * Modified oligonucleotides & DNA-RNA hybrids
   * Full-length genes
   * Gene sequencing
  
  
• PROTEOMICS
   * Custom peptides and modifications
   * Peptide conjugates
   * Peptide antibodies

We specialize in providing you with prompt, high quality and cost-effective support for research and drug discovery.  GenoMechanix technical staff and consultants, experts in synthetic chemistry and molecular biology, are ready to focus on your needs.  Our web based system allows the transfer of your sequences directly into our production process 24 hours a day.
 

Additional information:

  GENOMICS

Custom oligonucleotides

• Unmodified probes and primers
  * small probes/primers (< or  = 35 bases)
  * long DNAs (>120 bases) for gene
     synthesis/primer extension
  * varying lengths (30 - 100 bases) for other
     applications
  * single sequence and mixed bases
  
  
• Modifications
  * Biotin
  * Dyes
  * Terminal phosphate and amine
  * Unnatural bases
  * Phosphorothioates (S-oligo)
  
  
• Purification
  * Desalting
  * OPC Cartridge
  * RP/Ion-exchange HPLC
  * PAGE
  
  
• Amounts
  * 50 nM - 1µM
  * Preparations of  > 1µM for R&D
  * Preparations of  > 5µM for cell
     culture or animal studies

Gene sequencing

• Bacterial colony with plasmid or purified plasmid DNA
• PCR product

  PROTEOMICS

Custom peptides

• Milligram to gram quantities
   
• Purification to > 95% and fast turnaround
  
• Quality control
  * HPLC & Mass Spec.
  
  
• Complex modified peptides
  * Cyclized
  * Acetylated
  * Fomylated
  
  
• Unusual amino acids
  * Phospho-amino acids
  
• Discount on bulk orders

Anti-peptide antibodies - polyclonal & monoclonal

• Cross-linked/conjugated peptide immunogens
• Rabbit immunization, test bleed screening
• Whole sera/pure IgG
• Mice immunization, fusion, hybridoma screening
• Clones and culture supernatant for monoclonal antibodies
  

Quality control, turnaround &  technical support

• For most routine unmodified probes and primers, we ship within 24-36 hours from the time we receive your order.
• We perform QC on your products and the reagents we use.
• We have experts in peptide synthesis and modification chemistry as well as consultants with expertise in the design, synthesis and use of custom modified oligonucleotides.
• Our customer service department will promptly route your calls to our technical or operations staff.

Please contact us if you have further questions.